Cahyaning Puji Astuti, Melyana Nurul Widyawati, Sri Endang Pujiastuti


Background: Anemia is a major cause of bleeding due to iron deficiency. Iron tablets which contain 60 mg of Ferrous Sulphate and 0.25 mg of folic acid did not show good results in changing the body’s iron level and there are many perceived side effects. However, there is now exists an oral iron tablets in the form of available salt compounds of ferrous fumarate, ferrous sulphate, and ferrous gluconate. These tablets contain iron hydroxide polymaltose complex (III) or better known as IPC (Iron Polymaltose Complex) and have minimal side effects.

Aims: To understand the effect of IPC tablets in increasing the hemoglobin level in pregnant women with anemia.

Methods: This study used quantitative study with pre-experimental design, or experiments that have not been applied in real terms. This study used non-probability sampling technique and purposive sampling for the selected sample. The sample were 35 people based on the inclusion criteria. The design used was one group pre-test – post-test approach without the control group. The subjects undertook the anemia examination on the first day (pre-test) and afterwards were administered 100mg IPC tablets daily for the next 30 days. In the end of the intervention, the subjects were re-examined and the results were compared (post-test).

Results: The study showed that there is a significant increase of hemoglobin level in pregnant women with anemia with p value = 0.023 (p<0.05) after the intervention in the form of IPC tablet administration was conducted for 30 days.

Conclusion: The intervention performed in administration of IPC tablets for pregnant women with anemia showed a significant increase of hemoglobin level before and after the provision of IPC tablets. 

Full Text:



Indonesia KKR. Survei demografi kesehatan indonesia. In: Indonesia Kementerian kesehatan Republik, editor. Jakarta: Kementerian kesehatan Republik Indonesia 2012.

TR B. Maternal and child health situation in south east asia2012; 7(13).

Indonesia KKR. Rencana strategi kementerian kesehatan tahun 2015-2019. 2015.

RI KK. Survei demografi dan kesehatan indonesia 2012. Jakarta Kemenkes RI. 2013.

Kesehatan PJTD. Profil kesehatan provinsi jawa tengah tahun 2015. In: Kesehatan Dinas, editor. Semarang2015.

Kalaivani K. Prevalence & consequences of anaemia in pregnancy. Indian J Med Res. 2009;130(5):627-33.

Pavord S, Myers B, Robinson S, Allard S, Strong J, Oppenheimer C. Uk guidelines on the management of iron deficiency

in pregnancy. British journal of haematology. 2012;156(5):588-600.

Smid MC, Strauss RA. Maternal anemia. Maternal-Fetal Evidence Based Guidelines. 2017.

Saha L, Pandhi P, Gopalan S, Malhotra S, kumar Saha P. Comparison of efficacy, tolerability, and cost of iron polymaltose

complex with ferrous sulphate in the treatment of iron deficiency anemia in pregnant women. Medscape General Medicine.


Sari E. Perbandingan pemberian suplemen multi micronutrien dan tablet fe terhadap peningkatan hemoglobin, hematokrit pada ibu hamil di puskesmas prambanan klaten dan puskesmas prambanan sleman. MOTORIK Jurnal Ilmu Kesehatan (Journal Of Health Science). 2016;11(22).

Biesalski HK, Tinz J. Multivitamin/mineral supplements: Rationale and safety. Nutrition. 2017;36:60-6.

Taseer I-U-H, Mirbahar A, Safdar S, Awan Z. Anemia in pregnancy; related risk factors in under developed area. Professional Medical Journal. 2011;18(1).

Percy L, Mansour D, Fraser I. Iron deficiency and iron deficiency anaemia in women. Best Practice & Research Clinical

Obstetrics & Gynaecology. 2017;40:55-67.

Mulyani S. Hubungan antara status gizi dengan kadar hemoglobin pada ibu hamil trimester ii di puskesmas bandarharo

semarang utara. Karya Ilmiah S 1 Ilmu Keperawatan. 2013.

Sari E. Status gizi balita di posyandu mawar kelurahan darmokali surabaya. Keperawatan. 2017;6(1).

SyaBani IRN, Sumarmi S. Hubungan status gizi dengan kejadian anemia pada santriwati di pondok pesantren darul ulum

peterongan jombang. Jurnal Keperawatan Muhammadiyah. 2017;1(2).

Webster S, Chance B. At guelph volume 36 number 21 to number 31, 1992. 1992.

Eliagita C, Kuntjoro T, Sumarni S, Suwondo A, Hadisaputro S, Eliagita C, et al. Effect of consuming papaya (carica papaya

linn.) on the level of hemoglobin and hematocrit in pregnant women with anemia. Belitung Nursing Journal. 2017;3(2):120-5.

Percy L, Mansour D. Iron deficiency and iron‐deficiency anaemia in women's health. The Obstetrician & Gynaecologist.


Widyaningsih A, Setiyani O, Umaroh U, Sofro MAU, Amri F. Effect of consuming red dragon fruit (hylocereus

costaricensis) juice on the levels of hemoglobin and erythrocyte among pregnant women. Belitung Nursing Journal.


Moll R, Davis B. Iron, vitamin b 12 and folate. Medicine. 2017.

Chandra I, Sun L-z. Iron status and choice of iron therapy during pregnancy: Advantages and disadvantages. International

Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2017;4(5):1264-71.

Alaofè H, Burney J, Naylor R, Taren D. Prevalence of anaemia, deficiencies of iron and vitamin a and their determinants

in rural women and young children: A cross-sectional study in kalalé district of northern benin. Public health nutrition.


Retnorini DL, Widatiningsih S, Masini M. Pengaruh pemberian tablet fe dan sari kacang hijau terhadap kadar hemoglobin pada ibu hamil. JURNAL KEBIDANAN. 2017;6(12):8-16.


  • There are currently no refbacks.