Lia Dian Ayuningrum, Mardelia Astriani


Background: Premature infants are prone to loose skin stimulation through skin contact with the amniotic fluid and the uterine wall of the mother during the intrauterine phase. This situation becomes one of the decisive factors in the growth and development of infants’ nerves. In addition to the initial sensory deficiency, prematurity raises other related factors such as the absence of bonding between the mother and the newborns due to the need to remain in the neonatal intensive care unit (NICU). Prematurity also has adverse effects on the psychological and biological development of the children and the parents’ welfare. Aims: The aim of this study was to analyze the literature relating to holistic care in massage and music therapy for premature infants and summarize the benefits of both therapies.

Methods: The method used in finding articles was a literature review, using the keywords. Search was conducted electronically using several databases, including Pubmed, Science Direct, and Google Scholar 

Conclusion: Massage and music therapy have benefits for premature infants growth. Keywords: Premature infants, preterm, massage therapy, music therapy


Full Text:



Howson M, Kinney J. Lawn March of Dimes, PMNCH, Save the Children, WHO. Born Too Soon: The Global Action Report on Preterm Birth. World Health Organization, Geneva. 2012;17.

Sullivan MC, Hawes K, Winchester SB, Miller RJ. Developmental origins theory from prematurity to adult disease. Journal of Obstetric, Gynecologic, & Neonatal Nursing. 2008;37(2):158-64.

Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. The lancet. 2008;371(9606):75- 84.

Joseph K. The natural history of pregnancy: diseases of early and late gestation. BJOG: An International Journal of Obstetrics & Gynaecology. 2011;118(13):1617-29.

Ralser E, Mueller W, Haberland C, Fink FM, Gutenberger KH, Strobl R, et al. Rehospitalization in the first 2 years of life in children born preterm. Acta Paediatrica. 2012;101(1):e1-e5.

Im H, Kim E. Effect of Yakson and Gentle Human Touch versus usual care on urine stress hormones and behaviors in preterm infants: A quasi-experimental study. International Journal of Nursing Studies. 2009;46(4):450-8.

Flacking R, Lehtonen L, Thomson G, Axelin A, Ahlqvist S, Moran VH, et al. Closeness and separation in neonatal intensive care. Acta Paediatrica. 2012;101(10):1032-7.

Brett J, Staniszewska S, Newburn M, Jones N, Taylor L. A systematic mapping review of effective interventions for communicating with, supporting and providing information to parents of preterm infants. BMJ open. 2011:bmjopen-2010- 000023.

Karbasi SA, Golestan M, Fallah R, Golshan M, Dehghan Z. Effect of body massage on increase of low birth weight neonates growth parameters: A randomized clinical trial. Iranian journal of reproductive medicine. 2013;11(7):583.

Abdallah B, Badr LK, Hawwari M. The efficacy of massage on short and long term outcomes in preterm infants. Infant behavior and development. 2013;36(4):662-9.

AngJY,LuaJL,MathurA,ThomasR,AsmarBI,SavasanS,etal.Arandomizedplacebo-controlledtrialofmassagetherapy on the immune system of preterm infants. Pediatrics. 2012:peds. 2012-0196.

Yates CC, Mitchell AJ, Booth MY, Williams DK, Lowe LM, Hall RW. The effects of massage therapy to induce sleep in infants born preterm. Pediatric physical therapy: the official publication of the Section on Pediatrics of the American Physical Therapy Association. 2014;26(4):405.

Smith SL, Haley S, Slater H, Moyer-Mileur LJ. Heart rate variability during caregiving and sleep after massage therapy in preterm infants. Early human development. 2013;89(8):525-9.

LoewyJ.NICUmusictherapy:Songofkinascriticallullabyinresearchandpractice.AnnalsoftheNewYorkAcademyof Sciences. 2015;1337(1):178-85.

Loewy J, Stewart K, Dassler A-M, Telsey A, Homel P. The effects of music therapy on vital signs, feeding, and sleep in premature infants. Pediatrics. 2013;131(5):902-18.

Arnon S, Diamant C, Bauer S, Regev R, Sirota G, Litmanovitz I. Maternal singing during kangaroo care led to autonomic stability in preterm infants and reduced maternal anxiety. Acta Paediatrica. 2014;103(10):1039-44.

Pölkki T, Korhonen A. The effectiveness of music on pain among preterm infants in the NICU: A systematic review. JBI Database of Systematic Reviews and Implementation Reports. 2014;12(4):354-73.

ArayaA,EkanemE,ObembeT,Ongolo-ZogoC.AStructuredReviewontheEffectofMusicTherapyontheDevelopment of Preterm Babies. 2016.

AllenKA.MusictherapyintheNICU:isthereevidencetosupportintegrationforproceduralsupport?Advancesinneonatal care: official journal of the National Association of Neonatal Nurses. 2013;13(5).

Shabani F, Nayeri ND, Karimi R, Zarei K, Chehrazi M. Effects of music therapy on pain responses induced by blood sampling in premature infants: A randomized cross-over trial. Iranian journal of nursing and midwifery research. 2016;21(4):391.

Van Der Heijden MJ, Araghi SO, Jeekel J, Reiss IK, Hunink MM, Van Dijk M. Do hospitalized premature infants benefit from music interventions? A systematic review of randomized controlled trials. PloS one. 2016;11(9):e0161848.

Álvarez MJ, Fernández D, Gómez-Salgado J, Rodríguez-González D, Rosón M, Lapeña S. The effects of massage therapy in hospitalized preterm neonates: A systematic review. International Journal of Nursing Studies. 2017;69:119-36.

FieldT,DiegoM,Hernandez-ReifM.Preterminfantmassagetherapyresearch:areview.InfantBehaviorandDevelopment. 2010;33(2):115-24.

Sinha AG. Principle and Practice of Therapeutic Massage. Jaypee Brothers Medical Publisher. 2009.


Pallás Alonso C, Arriaga Redondo M. Nuevos aspectos en torno a la prematuridad. Evid Pediatr. 2008;4:26.

Robles-De-La-Torre G. The importance of the sense of touch in virtual and real environments. Ieee Multimedia.


Hikmah E. Pengaruh terapi sentuhan terhadap suhu dan frekuensi nadi bayi prematur yang dirawat di ruang perinatologi RSUD kabupaten Tangerang: Thesis tidak diterbitkan. Depok: Fakultas Ilmu Keperawatan Kekhususan Keperawatan Anak Universitas Indonesia; 2010.

Ahmed RG, Suliman GI, Elfakey WA, Salih KM, El-Amin EI, Ahmed WA, et al. Effect of tactile kinesthetic stimulation on preterm infants’ weight and length of hospital stay in Khartoum, Sudan. Saudi medical journal. 2015;36(2):196-9.

Fallah R, Karbasi SA, Golestan M, Fromandi M. Sunflower oil versus no oil moderate pressure massage leads to greater increases in weight in preterm neonates who are low birth weight. Early human development. 2013;89(9):769-72.

Alipour Z, Eskandari N, Hossaini SKE, Sangi S. Effects of music on physiological and behavioral responses of premature infants: a randomized controlled trial. Complementary therapies in clinical practice. 2013;19(3):128-32.

Dewi MP. Studi Metaanalisis: Musik untuk menurunkan stres. Jurnal Psikologi. 2015;36(2):106-15.


  • There are currently no refbacks.